Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 8/20 | 0.74 |
| ▸ | CDK1 | P06493 | 6/20 | 0.74 |
| ▸ | CDK7 | P50613 | 5/20 | 0.74 |
| ▸ | CDK9 | P50750 | 5/20 | 0.74 |
| ▸ | AURKA | O14965 | 4/20 | 0.74 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.74 |
| ▸ | CDK4 | P11802 | 4/20 | 0.74 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.53 |
| ▸ | JAK2 | O60674 | 2/20 | 0.53 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.53 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | ZAP70 | P43403 | 8/20 | 0.53 |
| ▸ | LCK | P06239 | 3/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.53 |
| ▸ | PRKCG | P05129 | 2/20 | 0.53 |
| ▸ | PRKCB | P05771 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2281574 | 0.89 | CDK2 (0.60) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2286640 | 0.87 | CDK2 (0.58) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL4159950 | 0.85 | CDK2 (1.00) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2286267 | 0.84 | CDK2 (0.57) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2284344 | 0.84 | CDK2 (0.81) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2283663 | 0.83 | CDK2 (0.61) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2289107 | 0.83 | CDK2 (0.80) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2282398 | 0.83 | CDK2 (0.58) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2287258 | 0.82 | MKNK2 (0.55) | CDK2CDK1CDK7CDK9AURKA | |
| SCHEMBL2281255 | 0.82 | CDK2 (0.54) | CDK2CDK1CDK7CDK9AURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030024-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, RDX | CDK2 2065/4885CDK1 793/4885CDK7 1953/4885 |
| US-20110195968-A1 | THIAZOLES AS FUNGICIDES | CYP4X1, CYP4Z1, CYP3A4 | CDK2 2144/4885CDK1 857/4885CDK7 1978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.