SCHEMBL22907608

SCHEMBL22907608

Cc1ccc2c(c1)c1cc(C)ccc1n2-c1ccc2c(c1)c1cc(-n3c4ccccc4c4cc(C#N)ccc43)ccc1n2-c1cccc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
MAPT P10636 2/20 0.34
LMNA P02545 1/20 0.34
PTGER4 P35408 2/20 0.34
NOTUM Q6P988 1/20 0.34
RPS6KB1 P23443 1/20 0.33
TP53 P04637 1/20 0.33
S1PR4 O95977 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
S1PR1 P21453 1/20 0.33
G6PD P11413 1/20 0.33
TDP2 O95551 4/20 0.32
USP14 P54578 2/20 0.32
MAT2A P31153 1/20 0.32
PLK1 P53350 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22907605 0.93 KDM4E (0.41) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL24987658 0.93 KDM4E (0.41) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL22907622 0.93 KDM4E (0.41) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL24988433 0.93 KDM4E (0.41) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL24987898 0.90 KDM4E (0.38) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL24986601 0.90 KDM4E (0.38) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL24985627 0.90 KDM4E (0.38) KDM4EATML3MBTL1PTGER4NOTUM
SCHEMBL22907507 0.90 L3MBTL1 (0.44) KDM4EATML3MBTL1MAPTLMNA
SCHEMBL25449262 0.90 L3MBTL1 (0.44) KDM4EATML3MBTL1MAPTLMNA
SCHEMBL24987858 0.89 KDM4E (0.39) KDM4EATML3MBTL1PTGER4NOTUM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020854-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-21 US disclosed