SCHEMBL22907617

SCHEMBL22907617

CC(C)(C)c1ccc2c(c1)c1cc(C(C)(C)C)ccc1n2-c1ccc2c(c1)Sc1cc(-n3c4ccccc4c4cc(C#N)ccc43)ccc1N2c1ccc2sc3ccccc3c2c1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.31
CSNK1D P48730 1/20 0.31
CSNK1G2 P78368 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22907586 0.93 G6PD (0.33)
SCHEMBL22907696 0.93 G6PD (0.33)
SCHEMBL22907580 0.92 PMM2 (0.33) RORC
SCHEMBL22907583 0.90 PMM2 (0.34) RORC
SCHEMBL22907697 0.90 G6PD (0.30)
SCHEMBL22907558 0.89 RORC (0.30) RORCCSNK1DCSNK1G2
SCHEMBL17115463 0.88 CSNK1D (0.37) RORCCSNK1DCSNK1G2
SCHEMBL17424671 0.88 CSNK1D (0.37) RORCCSNK1DCSNK1G2
SCHEMBL22907587 0.87 G6PD (0.32)
SCHEMBL22907582 0.86 PMM2 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020854-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-01-21 US disclosed