SCHEMBL22908271

SCHEMBL22908271

COC(=O)N(C)C(=O)CCC=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CNR1 P21554 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 1/20 0.31
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18522668 0.77 HPGD (0.36) MAPT
SCHEMBL19848759 0.75 NPC1 (0.31) TSHR
SCHEMBL19083864 0.73 MAPT (0.35) CNR1TSHRMAPT
SCHEMBL4721832 0.73
SCHEMBL24241911 0.73 CNR1 (0.33) CNR1
SCHEMBL23515288 0.72 MAPT (0.31) MAPT
SCHEMBL5664501 0.72
SCHEMBL6964767 0.72 MGAM (0.35) MEN1KMT2ATSHR
SCHEMBL23799051 0.71 MAPT (0.32) MAPT
SCHEMBL23543544 0.71 MAPT (0.32) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3766917-A1 HETEROBIFUNCTIONAL COMPOUND HAVING MONODISPERSED POLYETHYLENE GLYCOL IN MAIN CHAIN OR SIDE CHAIN NOF Corporation (JP) 2021-01-20 EP disclosed