SCHEMBL6964767

SCHEMBL6964767

CCC(=O)N(C)C(=O)OC

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SOAT1 P35610 1/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 6/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
FFAR3 O14843 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360045 0.78 ALDH1A1 (0.41) MGAMGAASIMGAM2MEN1
SCHEMBL11413136 0.78 ALDH1A1 (0.41) MGAMGAASIMGAM2SOAT1
SCHEMBL6965760 0.76 MGAM (0.32) MGAMGAASIMGAM2SOAT1
SCHEMBL22334350 0.76 MEN1 (0.31) MEN1KMT2A
SCHEMBL23904398 0.75 HDAC6 (0.41) SOAT1MEN1KMT2A
SCHEMBL18699689 0.75 MEN1 (0.34) MGAMGAASIMGAM2SOAT1
SCHEMBL27995532 0.73 ALOX15 (0.33) MGAMGAASIMGAM2SOAT1
SCHEMBL22908271 0.72 MEN1 (0.32) MEN1KMT2ATSHR
SCHEMBL19992256 0.71 ALDH1A1 (0.38) GAAMEN1KMT2AALDH1A1TSHR
SCHEMBL20387812 0.71 SOAT1 (0.32) SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US claimed
EP-0974582-B1 Process for the preparation of 4-substituted azetidinone derivatives TAKASAGO PERFUMERY CO LTD (JP) 2003-02-12 EP disclosed
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US disclosed
EP-0974582-A1 Process for the preparation of 4-substituted azetidinone derivatives Takasago International Corporation (JP) 2000-01-26 EP disclosed