Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908337 | 0.92 | PTGDR2 (0.46) | — | |
| SCHEMBL22908364 | 0.87 | NLRP3 (0.74) | NLRP3 | |
| SCHEMBL22908355 | 0.86 | NLRP3 (0.55) | NLRP3 | |
| SCHEMBL22908330 | 0.82 | — | — | |
| SCHEMBL22908324 | 0.81 | — | — | |
| SCHEMBL22908334 | 0.81 | NLRP3 (0.70) | NLRP3 | |
| SCHEMBL22908360 | 0.81 | — | — | |
| SCHEMBL29694521 | 0.80 | NLRP3 (0.60) | NLRP3 | |
| SCHEMBL22908323 | 0.79 | — | — | |
| SCHEMBL22908353 | 0.78 | ALDH1A1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011592-A1 | COMPOUNDS AS NLRP3 INFLAMMASOME INHIBITORS AND COMPOSITIONS AND USES THEREOF | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2021-01-21 | — | — | WO | disclosed |