Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.35 |
| ▸ | MELK | Q14680 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | ATXN2 | Q99700 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908434 | 0.92 | IGF1R (0.39) | P2RX7MAPK7MEN1KMT2AALDH1A1 | |
| SCHEMBL22908412 | 0.90 | P2RX7 (0.36) | P2RX7ENPP2ATXN2GRM5PIK3CA | |
| SCHEMBL22908411 | 0.90 | PIK3CA (0.39) | CHEK1CFTRMAPK7ENPP2ATXN2 | |
| SCHEMBL22908410 | 0.89 | PIK3CA (0.38) | CHEK1P2RX7ENPP2ATXN2PIK3CA | |
| SCHEMBL22908403 | 0.88 | GRM5 (0.43) | FFAR2CFTRMAPK7MEN1KMT2A | |
| SCHEMBL21361291 | 0.86 | FASN (0.37) | ENPP2ATXN2IRAK4 | |
| SCHEMBL21361292 | 0.86 | TSHR (0.40) | CHEK1MAPK7MEN1KMT2APIK3CA | |
| SCHEMBL22908449 | 0.84 | PIK3CA (0.38) | P2RX7ENPP2ATXN2PIK3CAMTOR | |
| SCHEMBL24120412 | 0.83 | FASN (0.36) | CHEK1CFTRMAPK7ENPP2ATXN2 | |
| SCHEMBL21361307 | 0.83 | CYP1A2 (0.38) | MAPK7MEN1KMT2APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |