Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22908434 | 0.90 | IGF1R (0.39) | MAPK7TSHRCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL22908404 | 0.88 | CHEK1 (0.36) | GRM5MAPK7SMN1; SMN2CYP3A4FFAR2 | |
| SCHEMBL21361301 | 0.86 | GRM5 (0.45) | GRM5SMN1; SMN2ARCYP3A4CYP2D6 | |
| SCHEMBL21361292 | 0.84 | TSHR (0.40) | MAPK7TSHRCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL24120370 | 0.84 | GRM5 (0.42) | GRM5MAPK7USP2TSHRCYP3A4 | |
| SCHEMBL22908402 | 0.83 | CYP2D6 (0.42) | USP2TSHRCYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL21361307 | 0.81 | CYP1A2 (0.38) | MAPK7TSHRCYP1A2CYP2C9CYP2D6 | |
| SCHEMBL22908414 | 0.80 | CYP1A2 (0.41) | GRM5TSHRCYP1A2CYP2C9CYP3A4 | |
| SCHEMBL22908406 | 0.80 | CYP2D6 (0.45) | USP2TSHRCYP1A2CYP2C9SMN1; SMN2 | |
| SCHEMBL22908538 | 0.79 | CCR8 (0.41) | USP2TSHRCYP1A2CYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009048-A1 | HERBICIDAL CYCLOHEXANEDIONE DERIVATIVES | SYNGENTA CROP PROTECTION AG (CH) | 2021-01-21 | — | — | WO | disclosed |