Sugi Predict

Sugi Predict / Compounds / SCHEMBL22909000

SCHEMBL22909000

SCHEMBL22909000

CCC(CCCCN)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 9/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ EPHX1 P07099 1/20 0.38
▸ NFKB1 P19838 1/20 0.35
▸ OPRM1 P35372 1/20 0.33
▸ GSR P00390 1/20 0.33
▸ CA12 O43570 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA3 P07451 1/20 0.33
▸ CA4 P22748 1/20 0.33
▸ CA6 P23280 1/20 0.33
▸ CA5A P35218 1/20 0.33
▸ CA7 P43166 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ CA14 Q9ULX7 1/20 0.33
▸ CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19519205 0.98 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL26079812 0.98 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL24058373 0.92 DNM1 (0.33) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL4857129 0.92 DNM1 (0.33) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL31333167 0.87 DNM1 (0.43) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL24347628 0.83 DNM1 (0.36) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL14812239 0.83 TRPV1 (0.41) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL21767042 0.83 DNM1 (0.42) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL10950660 0.83 DNM1 (0.48) DNM1MEN1KMT2AALDH1A1TSHR
SCHEMBL25752330 0.82 SLC7A5 (0.33) DNM1MEN1KMT2AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12246000-B2 Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides VILNIUS UNIVERSITY (LT) 2025-03-11 — — US disclosed
EP-3334464-B1 MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING MASSACHUSETTS GEN HOSPITAL (US) 2024-04-10 — — EP disclosed
US-20240000736-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES VILNIUS UNIVERSITY (LT) 2024-01-04 — — US disclosed
EP-4299062-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES Vilnius University (LT) 2024-01-03 — — EP disclosed
US-20210015948-A1 MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING THE GENERAL HOSPITAL CORPORATION 2021-01-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210015948-A1 MANGANESE-BASED CHELATE CONJUGATES FOR MOLECULAR MR IMAGING MPI, MAG, MNS1 DNM1 54/4885MEN1 26/4885KMT2A 880/4885
US-20240000736-A1 INHIBITION OF PROTEIN AMYLOID AGGREGATION USING FLUORINATED BENZENESULFONAMIDES APP, APBA1, IAPP DNM1 1983/4885MEN1 1754/4885KMT2A 3425/4885
US-12246000-B2 Inhibition of protein amyloid aggregation using fluorinated benzenesulfonamides APP, APBA1, IAPP DNM1 1983/4885MEN1 1754/4885KMT2A 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.