SCHEMBL14812239

SCHEMBL14812239

CCC(CCCCN)C(C)N

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.41
TRPA1 O75762 1/20 0.41
SPHK1 Q9NYA1 1/20 0.40
OPRM1 P35372 1/20 0.37
GSR P00390 1/20 0.37
DNM1 Q05193 8/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
EPHX1 P07099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9191832 0.93 TRPV1 (0.37) TRPV1TRPA1SPHK1OPRM1DNM1
SCHEMBL34890 0.85 TRPV1 (0.44) TRPV1TRPA1SPHK1OPRM1GSR
SCHEMBL31333167 0.85 DNM1 (0.43) GSRDNM1MEN1KMT2AALDH1A1
SCHEMBL22909000 0.83 DNM1 (0.38) OPRM1GSRDNM1MEN1KMT2A
SCHEMBL6692572 0.83 OPRM1 (0.56) TRPV1TRPA1SPHK1OPRM1ALDH1A1
SCHEMBL10071347 0.82
SCHEMBL4584791 0.82 SPHK1 (0.57) TRPV1TRPA1SPHK1OPRM1DNM1
SCHEMBL24347628 0.81 DNM1 (0.36) OPRM1GSRDNM1MEN1KMT2A
SCHEMBL14811809 0.81 GSR (0.37) OPRM1GSRDNM1MEN1KMT2A
SCHEMBL20871505 0.81 SPHK1 (0.56) TRPV1TRPA1SPHK1OPRM1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10597494-B2 Thermoplastic (co)polyimides and synthesis methods RHODIA OPERATIONS (FR) 2020-03-24 US disclosed
EP-2758449-B1 THERMOPLASTIC (CO)POLYIMIDES AND SYNTHESIS METHODS RHODIA OPERATIONS (FR) 2019-01-16 EP disclosed
US-20180155498-A1 THERMOPLASTIC (CO)POLYIMIDES AND SYNTHESIS METHODS RHODIA OPERATIONS (FR) 2018-06-07 US disclosed
US-20140342628-A1 THERMOPLASTIC (CO)POLYIMIDES AND SYNTHESIS METHODS RHODIA OPERATIONS (FR) 2014-11-20 US disclosed
EP-2758449-A1 THERMOPLASTIC (CO)POLYIMIDES AND SYNTHESIS METHODS Rhodia Operations (FR) 2014-07-30 EP disclosed
CN-103827174-A Thermoplastic (co) polyimide and its synthesis RHODIA OPERATIONS 2014-05-28 CN disclosed
WO-2013041530-A1 THERMOPLASTIC (CO)POLYIMIDES AND SYNTHESIS METHODS RHODIA OPERATIONS (FR) 2013-03-28 WO disclosed