Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29513197 | 1.00 | MAPT (0.54) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL30765073 | 0.90 | ALDH1A1 (0.51) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL22908996 | 0.90 | ALDH1A1 (0.51) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL22908985 | 0.85 | ALDH1A1 (0.53) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL22909056 | 0.84 | ALDH1A1 (0.55) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL29513048 | 0.84 | ALDH1A1 (0.55) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL23112012 | 0.84 | ALDH1A1 (0.69) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL22905016 | 0.84 | ALDH1A1 (0.69) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL29443017 | 0.84 | ALDH1A1 (0.69) | MAPTGAALMNAL3MBTL1NPSR1 | |
| SCHEMBL23112085 | 0.83 | ALDH1A1 (0.49) | MAPTGAALMNAL3MBTL1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999185-B1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | CTXT PTY LTD (AU) | 2023-08-30 | — | — | EP | disclosed |
| WO-2021009365-A1 | BENZOTHIOPHENE, THIENOPYRIDINE AND THIENOPYRIMIDINE DERIVATIVES FOR THE MODULATION OF STING | CTXT PTY LIMITED (AU) | 2021-01-21 | — | — | WO | disclosed |