Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671297 | 1.00 | CA1 (0.31) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL29729067 | 0.86 | CA1 (0.31) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22909594 | 0.79 | F2 (0.38) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL29899443 | 0.79 | F2 (0.38) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL29729057 | 0.79 | CA1 (0.33) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL22909271 | 0.76 | CA1 (0.43) | CA1CA2HDAC3HDAC11HDAC8 | |
| SCHEMBL22909160 | 0.75 | MAPT (0.36) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL29729048 | 0.75 | CA1 (0.31) | CA1CA2CA9HDAC3HDAC11 | |
| SCHEMBL22909157 | 0.75 | GSTO1 (0.32) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29899485 | 0.75 | CA1 (0.37) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |