Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29729037 | 1.00 | GSTO1 (0.32) | GSTO1CA1CA2CA9LMNA | |
| SCHEMBL24459979 | 0.79 | CA1 (0.34) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29899443 | 0.79 | F2 (0.38) | CA1CA2CA9LMNASMN1; SMN2 | |
| SCHEMBL22909594 | 0.79 | F2 (0.38) | CA1CA2CA9LMNASMN1; SMN2 | |
| SCHEMBL29671308 | 0.78 | HDAC3 (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL22909278 | 0.78 | HDAC3 (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL22909271 | 0.76 | CA1 (0.43) | CA1CA2LMNASMN1; SMN2CA12 | |
| SCHEMBL28762129 | 0.76 | CA1 (0.54) | CA1CA2CA9CA12CA7 | |
| SCHEMBL29899453 | 0.75 | CA1 (0.37) | CA1CA2CA9CA12CA7 | |
| SCHEMBL22909259 | 0.75 | CA1 (0.31) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |