Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831479 | 0.98 | ALDH1A1 (0.50) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL25539403 | 0.83 | TSHR (0.47) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29728648 | 0.83 | ALDH1A1 (0.53) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL238269 | 0.83 | ALDH1A1 (0.53) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL23043619 | 0.80 | ALDH1A1 (0.59) | MAPK1ALDH1A1SMN1; SMN2MAPTPKM | |
| SCHEMBL8068958 | 0.80 | ALDH1A1 (0.55) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8074290 | 0.80 | ALDH1A1 (0.55) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL19998621 | 0.80 | TSHR (0.57) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6204539 | 0.80 | TSHR (0.49) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7918440 | 0.78 | MAPT (0.44) | MAPK1TSHRALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |