Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA7 | P43166 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.38 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.38 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671317 | 1.00 | CA2 (0.53) | CA2CA1CA13CA12CA7 | |
| SCHEMBL22909364 | 0.89 | CA2 (0.54) | CA2CA1CA13CA12CA7 | |
| SCHEMBL22909578 | 0.89 | CA2 (0.61) | CA2CA1CA13CA12CA7 | |
| SCHEMBL22909494 | 0.87 | CA12 (0.73) | CA2CA1CA13CA12CA7 | |
| SCHEMBL29671248 | 0.87 | CA12 (0.73) | CA2CA1CA13CA12CA7 | |
| SCHEMBL29671275 | 0.85 | CA2 (0.48) | CA2CA1CA13CA12CA7 | |
| SCHEMBL29671244 | 0.80 | CA1 (0.51) | CA2CA1CA13CA12CA7 | |
| SCHEMBL22909472 | 0.80 | CA1 (0.51) | CA2CA1CA13CA12CA7 | |
| SCHEMBL22909154 | 0.75 | NPC1 (0.47) | CA2CA1CA13CA12CA7 | |
| SCHEMBL29671321 | 0.75 | NPC1 (0.47) | CA2CA1CA13CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |