Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.73 |
| ▸ | CA1 | P00915 | 3/20 | 0.73 |
| ▸ | CA2 | P00918 | 3/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | CA7 | P43166 | 2/20 | 0.73 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671248 | 1.00 | CA12 (0.73) | CA12CA1CA2CA9CA7 | |
| SCHEMBL29671317 | 0.87 | CA2 (0.53) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22909392 | 0.87 | CA2 (0.53) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22380992 | 0.84 | CA2 (1.00) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22909364 | 0.84 | CA2 (0.54) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22909578 | 0.84 | CA2 (0.61) | CA12CA1CA2CA9CA7 | |
| SCHEMBL29671244 | 0.83 | CA1 (0.51) | CA12CA1CA2CA9CA7 | |
| SCHEMBL22909472 | 0.83 | CA1 (0.51) | CA12CA1CA2CA9CA7 | |
| SCHEMBL29671275 | 0.81 | CA2 (0.48) | CA12CA1CA2CA9CA7 | |
| SCHEMBL31124350 | 0.80 | CA2 (0.87) | CA12CA1CA2CA9CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |