SCHEMBL22909458 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	CA1	P00915	17/20	0.61

▸	CA2	P00918	17/20	0.61

▸	MMP1	P03956	1/20	0.59

▸	MMP2	P08253	1/20	0.59

▸	MMP9	P14780	1/20	0.59

▸	MMP8	P22894	1/20	0.59

▸	MMP13	P45452	1/20	0.59

▸	F2	P00734	2/20	0.46

▸	PRSS1	P07477	2/20	0.46

▸	PRSS2	P07478	2/20	0.46

▸	PRSS3	P35030	2/20	0.46

▸	CA12	O43570	2/20	0.46

▸	CA7	P43166	2/20	0.46

▸	CA13	Q8N1Q1	2/20	0.46

▸	SLC1A3	P43003	1/20	0.39

▸	SLC1A2	P43004	1/20	0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2347469	0.85	CA1 (0.71)	CA1CA2MMP1MMP2MMP9
SCHEMBL22909363	0.83	CA1 (0.50)	CA1CA2MMP1MMP2MMP9
SCHEMBL4175368	0.80	CA1 (0.58)	CA1CA2MMP1MMP2MMP9
SCHEMBL18426124	0.78	CA1 (0.62)	CA1CA2MMP1MMP2MMP9
SCHEMBL12386318	0.76	CA1 (0.60)	CA1CA2MMP1MMP2MMP9
SCHEMBL8229515	0.74	CA1 (1.00)	CA1CA2MMP1MMP2MMP9
SCHEMBL25737830	0.74	CA1 (0.58)	CA1CA2MMP1MMP2MMP9
SCHEMBL24842829	0.72	CA1 (0.56)	CA1CA2MMP1MMP2MMP9
SCHEMBL12129751	0.72	CA1 (0.56)	CA1CA2MMP1MMP2MMP9
SCHEMBL13462910	0.72	CA1 (0.56)	CA1CA2MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2021009568-A1	BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF	2692372 ONTARIO, INC. (CA)	2021-01-21	—	—	WO	disclosed