Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 11/20 | 0.50 |
| ▸ | CA2 | P00918 | 11/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29899461 | 0.84 | CA1 (0.48) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22909458 | 0.83 | CA1 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL352595 | 0.73 | CA1 (0.44) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL23409112 | 0.71 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29671223 | 0.71 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL24459976 | 0.71 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL29671269 | 0.71 | CA1 (0.41) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL22909432 | 0.71 | CA1 (0.39) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28388482 | 0.70 | CA1 (0.39) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2347469 | 0.69 | CA1 (0.71) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |