Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671217 | 1.00 | TAS2R14 (0.46) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL22909284 | 0.91 | TAS2R14 (0.47) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL29671272 | 0.91 | TAS2R14 (0.47) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL29671234 | 0.88 | TAS2R14 (0.47) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL22909525 | 0.88 | TAS2R14 (0.47) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL28762040 | 0.86 | PGR (0.45) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL29671209 | 0.86 | PGR (0.45) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL22909285 | 0.86 | TAS2R14 (0.46) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL29671198 | 0.86 | TAS2R14 (0.46) | TAS2R14CNR2CNR1PGRALDH1A1 | |
| SCHEMBL28762131 | 0.85 | TAS2R14 (0.45) | TAS2R14CNR2CNR1PGRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114502533-A | Benzenesulfonamide derivatives and use thereof | 2692372安大略公司 | 2022-05-13 | — | — | CN | disclosed |
| WO-2021009568-A1 | BENZENESULFONAMIDE DERIVATIVES AND USES THEREOF | 2692372 ONTARIO, INC. (CA) | 2021-01-21 | — | — | WO | disclosed |