⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21175421 | 1.00 | — | — | |
| SCHEMBL26767863 | 0.80 | — | — | |
| SCHEMBL21175176 | 0.79 | GLP1R (0.32) | — | |
| SCHEMBL22909671 | 0.73 | ALDH1A1 (0.33) | — | |
| SCHEMBL28952319 | 0.72 | GLP1R (0.32) | — | |
| SCHEMBL21175252 | 0.72 | GLP1R (0.32) | — | |
| SCHEMBL28952435 | 0.70 | NR1H2 (0.33) | — | |
| SCHEMBL31692192 | 0.68 | LMNA (0.34) | — | |
| SCHEMBL31692208 | 0.65 | CHRM2 (0.34) | — | |
| SCHEMBL38651835 | 0.65 | F12 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017176-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-01-21 | — | — | US | disclosed |