Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 3/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21175241 | 0.91 | ALDH1A1 (0.37) | MEN1KMT2ANTRK1ALDH1A1 | |
| SCHEMBL20014957 | 0.91 | NTRK1 (0.44) | MEN1KMT2ANTRK1C5AR1MAPT | |
| SCHEMBL21183751 | 0.87 | NTRK1 (0.39) | LMNAPABPC1ATMSMN1; SMN2NTRK1 | |
| SCHEMBL20015139 | 0.82 | C5AR1 (0.42) | NTRK1C5AR1THRB | |
| SCHEMBL20014985 | 0.82 | C5AR1 (0.42) | MEN1KMT2ANTRK1C5AR1MAPT | |
| SCHEMBL21175362 | 0.82 | NTRK1 (0.38) | NTRK1ALDH1A1C5AR1 | |
| SCHEMBL21175270 | 0.82 | ALDH1A1 (0.36) | NTRK1ALDH1A1 | |
| SCHEMBL30178379 | 0.78 | NTRK1 (0.43) | NTRK1C5AR1THRB | |
| SCHEMBL20015365 | 0.78 | NTRK1 (0.43) | NTRK1C5AR1THRB | |
| SCHEMBL21175154 | 0.78 | NTRK1 (0.41) | MEN1KMT2ANTRK1ALDH1A1C5AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017176-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2021-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017176-A1 | PYRAZOLOPYRIDINE DERIVATIVE HAVING GLP-1 RECEPTOR AGONIST EFFECT | GLP1R, GPR119, GIPR | LMNA 4197/4885PABPC1 2517/4885ATM 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.