Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PLAU | P00749 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911505 | 0.82 | NPC1 (0.61) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL12700350 | 0.78 | ALDH1A1 (0.58) | SMORAB9AMEN1KMT2ANPC1 | |
| SCHEMBL24860928 | 0.78 | CYP3A4 (0.52) | SMORAB9AMEN1KMT2ANPC1 | |
| SCHEMBL21579436 | 0.74 | SMO (0.51) | SMOMEN1KMT2APOLBHTT | |
| SCHEMBL14363351 | 0.74 | KMT2A (0.56) | RAB9AMEN1KMT2ANPC1POLB | |
| SCHEMBL18132360 | 0.73 | SMO (0.60) | SMOMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL15928756 | 0.73 | ALDH1A1 (0.72) | SMOMEN1KMT2APOLBHPGD | |
| SCHEMBL14112955 | 0.72 | HPGD (0.69) | RAB9AMEN1KMT2ANPC1LMNA | |
| SCHEMBL7764478 | 0.72 | HPGD (0.74) | MEN1KMT2ALMNATP53HTT | |
| SCHEMBL10282271 | 0.72 | NPC1 (0.80) | RAB9AMEN1KMT2ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484481-B1 | METHODS FOR USE IN THE TREATMENT OF CLOSTRIDIUM DIFFICILE | SCRIPPS RESEARCH INST (US) | 2021-01-20 | — | — | EP | disclosed |