SCHEMBL7764478

SCHEMBL7764478

Cc1cccc(C(=O)Nc2ccccc2)c1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.74
PLAU P00749 2/20 0.67
F2 P00734 1/20 0.67
F10 P00742 1/20 0.67
PLG P00747 1/20 0.67
PLAT P00750 1/20 0.67
KLK1 P06870 1/20 0.67
KLK5 Q9Y337 1/20 0.67
P2RX1 P51575 1/20 0.62
KMT2A Q03164 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HSD17B10 Q99714 2/20 0.61
MEN1 O00255 2/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
HTT P42858 1/20 0.61
KCNK3 O14649 1/20 0.60
KCNK9 Q9NPC2 1/20 0.60
KDR P35968 1/20 0.60
ALDH1A1 P00352 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7067826 0.87 MEN1 (0.71) HPGDKMT2AKDM4EHSD17B10MEN1
SCHEMBL21993 0.85 HPGD (1.00) HPGDKMT2AKDM4EHSD17B10MEN1
SCHEMBL2700622 0.85 SMN1; SMN2 (0.67) HPGDPLAUF2F10PLG
SCHEMBL2702708 0.85 PLAU (0.66) HPGDPLAUF2F10PLG
SCHEMBL4138863 0.84 HPGD (0.77) HPGDKMT2AKDM4EHSD17B10MEN1
SCHEMBL2701827 0.83 P2RX1 (0.63) HPGDPLAUF2F10PLG
SCHEMBL2703391 0.83 FADS1 (0.67) PLAUF2F10PLGPLAT
SCHEMBL2698800 0.83 P2RX1 (0.67) HPGDPLAUF2F10PLG
SCHEMBL28994974 0.83 HPGD (0.74) HPGDKMT2AKDM4EHSD17B10MEN1
SCHEMBL845143 0.82 TERT (0.80) HPGDKLK1KLK5P2RX1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7214464-B2 High speed positive-working photothermographic radiographic film EASTMAN KODAK COMPANY (US) 2007-05-08 US disclosed
US-7214464-B2 High speed positive-working photothermographic radiographic film EASTMAN KODAK COMPANY (US) 2007-05-08 US disclosed
US-7198889-B2 High-speed positive-working photothermographic system comprising an accelerating agent EASTMAN KODAK COMPANY (US) 2007-04-03 US disclosed
US-7198889-B2 High-speed positive-working photothermographic system comprising an accelerating agent EASTMAN KODAK COMPANY (US) 2007-04-03 US disclosed
US-7183024-B2 High-speed positive-working photothermographic system EASTMAN KODAK COMPANY (US) 2007-02-27 US disclosed
US-7183024-B2 High-speed positive-working photothermographic system EASTMAN KODAK COMPANY (US) 2007-02-27 US disclosed
WO-2001093642-A1 PHOSPHORESCENT ORGANIC LIGHT EMITTING DEVICES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2001-12-06 WO disclosed
WO-1994022417-A1 AN ORAL HYGIENE PRETREATMENT COMPOSITION SMITHKLINE BEECHAM PLC (GB) 1994-10-13 WO disclosed