⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29596517 | 0.76 | HDAC1 (0.31) | — | |
| SCHEMBL22911964 | 0.76 | HDAC1 (0.31) | — | |
| SCHEMBL14299556 | 0.72 | GRM5 (0.31) | — | |
| SCHEMBL22911956 | 0.71 | — | — | |
| SCHEMBL15570420 | 0.68 | — | — | |
| SCHEMBL8973225 | 0.68 | ADRA2A (0.36) | — | |
| SCHEMBL1163938 | 0.67 | CSNK1A1 (0.39) | — | |
| SCHEMBL708713 | 0.67 | FFAR1 (0.42) | — | |
| SCHEMBL20929102 | 0.65 | GRM5 (0.30) | — | |
| SCHEMBL18913628 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388990-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. | 2022-12-08 | — | — | US | disclosed |
| EP-3999498-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114401955-A | Inhibitors of cyclin dependent kinases | 金耐特生物制药公司 | 2022-04-26 | — | — | CN | disclosed |
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |