Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911964 | 1.00 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL22911955 | 0.76 | — | — | |
| SCHEMBL23627444 | 0.73 | NOS3 (0.31) | — | |
| SCHEMBL20929102 | 0.73 | GRM5 (0.30) | — | |
| SCHEMBL1349094 | 0.72 | HSP90AA1 (0.35) | — | |
| SCHEMBL22911966 | 0.71 | — | — | |
| SCHEMBL651271 | 0.69 | NOS3 (0.31) | — | |
| SCHEMBL1137069 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL29350657 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL5290860 | 0.67 | GRM4 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3999498-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2022-05-25 | — | — | EP | disclosed |
| CN-114401955-A | Inhibitors of cyclin dependent kinases | 金耐特生物制药公司 | 2022-04-26 | — | — | CN | disclosed |