Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 17/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911893 | 0.82 | GRM4 (0.55) | GRM4HRH4HTR2CPRMT3 | |
| SCHEMBL22911985 | 0.80 | KMT2A (0.40) | GRM4 | |
| SCHEMBL22911878 | 0.79 | GRM4 (0.47) | GRM4PRMT3 | |
| SCHEMBL24704570 | 0.77 | GRM4 (0.46) | GRM4PRMT3 | |
| SCHEMBL22911912 | 0.74 | GRM4 (0.48) | GRM4PRMT3 | |
| SCHEMBL22911907 | 0.74 | GRM4 (0.49) | GRM4HRH4HTR2C | |
| SCHEMBL22911990 | 0.74 | HRH4 (0.41) | GRM4HRH4HTR2C | |
| SCHEMBL29003692 | 0.70 | HRH4 (0.73) | HRH4HTR2C | |
| SCHEMBL30275021 | 0.70 | HRH4 (0.73) | HRH4HTR2C | |
| SCHEMBL19794606 | 0.69 | GRM4 (1.00) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |