Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22911959 | 0.80 | TGM2 (0.47) | LMNAPDGFRBMAPK14LCKKIT | |
| SCHEMBL22912012 | 0.80 | GRM4 (0.52) | GRM4 | |
| SCHEMBL22912018 | 0.75 | KMT2A (0.49) | KMT2ALMNAMAPK14HPGDSMN1; SMN2 | |
| SCHEMBL29596511 | 0.75 | KMT2A (0.49) | KMT2ALMNAMAPK14HPGDSMN1; SMN2 | |
| SCHEMBL2947965 | 0.73 | HPGD (0.46) | KMT2ALMNAHPGDSMN1; SMN2MEN1 | |
| SCHEMBL22911981 | 0.72 | ALDH1A1 (0.47) | KMT2ALMNASMN1; SMN2POLBGAA | |
| SCHEMBL29648045 | 0.72 | KMT2A (0.69) | KMT2ALMNAPDGFRBHPGDSMN1; SMN2 | |
| SCHEMBL22440038 | 0.72 | KMT2A (0.69) | KMT2ALMNAPDGFRBHPGDSMN1; SMN2 | |
| SCHEMBL1268259 | 0.70 | KMT2A (0.67) | KMT2ALMNAPDGFRBHPGDSMN1; SMN2 | |
| SCHEMBL22440034 | 0.70 | KMT2A (0.54) | KMT2ALMNAPDGFRBHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |