Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | C1S | P09871 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29596511 | 1.00 | KMT2A (0.49) | KMT2ALMNAHPGDC1SALDH1A1 | |
| SCHEMBL22440038 | 0.82 | KMT2A (0.69) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL29648045 | 0.82 | KMT2A (0.69) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL1268259 | 0.80 | KMT2A (0.67) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL2947965 | 0.80 | HPGD (0.46) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL22911991 | 0.77 | HPGD (0.58) | KMT2AHPGDALDH1A1POLBMAPT | |
| SCHEMBL22440034 | 0.76 | KMT2A (0.54) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL31572208 | 0.76 | KMT2A (0.54) | KMT2ALMNAHPGDALDH1A1MAPT | |
| SCHEMBL22911907 | 0.76 | GRM4 (0.49) | KMT2AALDH1A1POLBMAPTMEN1 | |
| SCHEMBL22911981 | 0.76 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |