Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24704588 | 0.82 | MAT2A (0.41) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL22911949 | 0.80 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1HTTMAPT | |
| SCHEMBL13701031 | 0.77 | TSHR (0.45) | ALDH1A1LMNAHTTMAPTACHE | |
| SCHEMBL28729733 | 0.77 | RHOA (0.41) | ALDH1A1LMNAHTTMAPTPOLB | |
| SCHEMBL2945973 | 0.76 | MAPK14 (0.61) | ALDH1A1LMNAMAPK1HTTMAPT | |
| SCHEMBL22912018 | 0.76 | KMT2A (0.49) | ALDH1A1LMNAMAPTGAAPOLB | |
| SCHEMBL29596511 | 0.76 | KMT2A (0.49) | ALDH1A1LMNAMAPTGAAPOLB | |
| Trifluoroacetic Acid SCHEMBL28729299 | 0.74 | C1S (0.45) | ALDH1A1LMNAHTTMAPTTDP1 | |
| Trifluoroacetic Acid SCHEMBL29595902 | 0.74 | C1S (0.45) | ALDH1A1LMNAHTTMAPTTDP1 | |
| Trifluoroacetic Acid SCHEMBL28729295 | 0.74 | C1S (0.45) | ALDH1A1LMNAHTTMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021011796-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | KINNATE BIOPHARMA INC. (US) | 2021-01-21 | — | — | WO | disclosed |