Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | SDHB | P21912 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29976084 | 0.86 | MEN1 (0.57) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL20985636 | 0.86 | MEN1 (0.57) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL19805752 | 0.85 | MEN1 (0.53) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL29975831 | 0.80 | SDHB (0.72) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL19805620 | 0.80 | SDHB (0.72) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL29976351 | 0.80 | MEN1 (0.51) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL19806057 | 0.80 | MEN1 (0.51) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL22912193 | 0.78 | SDHB (0.60) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL22912197 | 0.78 | MEN1 (0.49) | MEN1KMT2ASDHBALDH1A1MAPK1 | |
| SCHEMBL3557728 | 0.78 | LMNA (0.55) | MEN1KMT2ASDHBALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |