Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 17/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | STAT3 | P40763 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | STAT1 | P42224 | 2/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307457 | 0.88 | SDHB (0.56) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28306295 | 0.87 | SDHB (0.47) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28307441 | 0.87 | SDHB (0.56) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28307462 | 0.85 | SDHB (0.59) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL19805651 | 0.85 | SDHB (0.42) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL30526106 | 0.85 | SDHB (0.59) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28306261 | 0.85 | SDHB (0.58) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL19805836 | 0.84 | SDHB (0.59) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28875024 | 0.84 | SDHB (0.59) | SDHBNPSR1RAB9ATP53HPGD | |
| SCHEMBL28306389 | 0.84 | SDHB (0.49) | SDHBNPSR1RAB9ATP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |