Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 14/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | STAT3 | P40763 | 4/20 | 0.48 |
| ▸ | MITF | O75030 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | STAT1 | P42224 | 2/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307462 | 1.00 | SDHB (0.59) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28307452 | 0.90 | SDHB (0.48) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28306261 | 0.89 | SDHB (0.58) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28307460 | 0.88 | SDHB (0.45) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28307434 | 0.88 | SDHB (0.63) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28306444 | 0.87 | SDHB (0.54) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28306456 | 0.87 | SDHB (0.64) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28306448 | 0.87 | SDHB (0.60) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28307457 | 0.86 | SDHB (0.56) | SDHBNPSR1HPGDHTTLMNA | |
| SCHEMBL28307456 | 0.86 | SDHB (0.43) | SDHBNPSR1HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250210201-A1 | METHODS FOR STRATIFICATION OF PARKINSON'S DISEASE PATIENTS, SYSTEMS AND USES THEREOF | UNIV LUXEMBOURG (LU) | 2025-06-26 | — | — | US | disclosed |
| EP-4493725-A1 | METHODS FOR STRATIFICATION OF PARKINSON'S DISEASE PATIENTS, SYSTEMS AND USES THEREOF | Université du Luxembourg (LU) | 2025-01-22 | — | — | EP | disclosed |
| WO-2023174989-A1 | METHODS FOR STRATIFICATION OF PARKINSON'S DISEASE PATIENTS, SYSTEMS AND USES THEREOF | UNIVERSITÉ DU LUXEMBOURG (LU) | 2023-09-21 | — | — | WO | disclosed |
| US-11725000-B2 | Apoptosis inhibitors | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725000-B2 | Apoptosis inhibitors | BAX, SDHA, SDHB | SDHB 3/4885NPSR1 4745/4885HPGD 208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.