Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806016 | 0.86 | FNTA (0.35) | ALDH1A1MAOBFNTAFNTBKCNH2 | |
| SCHEMBL22912308 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL19806014 | 0.81 | FNTA (0.36) | ALDH1A1MAOBIDO1FNTAFNTB | |
| SCHEMBL19806129 | 0.79 | FNTA (0.35) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL22912282 | 0.75 | IDO1 (0.43) | ALDH1A1MAOBIDO1FNTAFNTB | |
| SCHEMBL28551552 | 0.70 | IDO1 (0.41) | ALDH1A1MAOBPARP15PARP10PARP14 | |
| SCHEMBL19805918 | 0.70 | IDO1 (0.43) | ALDH1A1MAOBIDO1FNTAFNTB | |
| SCHEMBL22912305 | 0.69 | IDO1 (0.36) | MAOBIDO1FFAR1 | |
| SCHEMBL21019820 | 0.67 | MEN1 (0.36) | ALDH1A1MAOBIDO1FNTAFNTB | |
| SCHEMBL5509988 | 0.63 | L3MBTL1 (0.40) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |