Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 13/20 | 0.87 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | STAT3 | P40763 | 3/20 | 0.49 |
| ▸ | STAT1 | P42224 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806001 | 0.93 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL20985646 | 0.84 | SDHB (0.86) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL29976150 | 0.84 | SDHB (0.86) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL20985729 | 0.83 | SDHB (0.81) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL29976258 | 0.82 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL20985736 | 0.82 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL20985622 | 0.81 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL30526080 | 0.81 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL20985619 | 0.81 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT | |
| SCHEMBL30526115 | 0.81 | SDHB (1.00) | SDHBSMN1; SMN2TP53POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |