Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806025 | 0.86 | SDHB (0.43) | MAPTTP53SMN1; SMN2MAPK10HIF1A | |
| SCHEMBL21019760 | 0.78 | SDHB (0.40) | MAPTTP53ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21019951 | 0.76 | PDE5A (0.43) | MAPTALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL19805950 | 0.76 | MAPK10 (0.42) | MAPTALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL26312785 | 0.76 | SDHB (0.41) | ALDH1A1MAPK10HIF1A | |
| SCHEMBL23897443 | 0.74 | EGFR (0.38) | MAPTTP53RXFP1ALDH1A1HPGD | |
| SCHEMBL21020127 | 0.74 | SDHB (0.40) | MAPTTP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22912251 | 0.74 | EGFR (0.37) | TP53RXFP1ALDH1A1HPGDKDM4E | |
| SCHEMBL19805630 | 0.73 | EGFR (0.35) | ALDH1A1HPGDKDM4ENPSR1LMNA | |
| SCHEMBL21019476 | 0.73 | SDHB (0.39) | MAPTTP53ALDH1A1SMN1; SMN2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |