Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22912303 | 0.89 | VCP (0.33) | VCP | |
| SCHEMBL22912304 | 0.88 | HSD17B10 (0.35) | VCP | |
| SCHEMBL19806015 | 0.87 | PFKFB3 (0.31) | PFKFB3S1PR1DRD3S1PR3 | |
| SCHEMBL29976521 | 0.87 | PFKFB3 (0.31) | PFKFB3S1PR1DRD3S1PR3 | |
| SCHEMBL21019945 | 0.86 | BRD4 (0.32) | VCP | |
| SCHEMBL23897443 | 0.85 | EGFR (0.38) | VCP | |
| SCHEMBL19806106 | 0.85 | VCP (0.32) | VCP | |
| SCHEMBL19806024 | 0.84 | EGFR (0.35) | VCP | |
| SCHEMBL22912255 | 0.83 | VCP (0.33) | VCP | |
| SCHEMBL22912294 | 0.81 | VCP (0.33) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |