Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | GNRHR | P30968 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806096 | 0.88 | SDHB (0.35) | VCPMAPK14 | |
| SCHEMBL19805939 | 0.87 | MAPK14 (0.32) | P2RX7GNRHRMAPK14 | |
| SCHEMBL29976175 | 0.87 | MAPK14 (0.32) | P2RX7GNRHRMAPK14 | |
| SCHEMBL19805941 | 0.87 | SDHB (0.32) | P2RX7GNRHRMAPK14 | |
| SCHEMBL29976196 | 0.87 | SDHB (0.32) | P2RX7GNRHRMAPK14 | |
| SCHEMBL19806024 | 0.83 | EGFR (0.35) | VCPP2RX7LMNAMAPTHTT | |
| SCHEMBL19805938 | 0.83 | BRD4 (0.34) | VCPGNRHR | |
| SCHEMBL22912304 | 0.83 | HSD17B10 (0.35) | VCP | |
| SCHEMBL22912303 | 0.83 | VCP (0.33) | VCPGNRHR | |
| SCHEMBL19806106 | 0.81 | VCP (0.32) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |