Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23897443 | 0.90 | EGFR (0.38) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL30526072 | 0.87 | GNRHR (0.33) | GNRHRPDE2ATP53 | |
| SCHEMBL19806125 | 0.87 | GNRHR (0.33) | GNRHRPDE2ATP53 | |
| SCHEMBL19806024 | 0.87 | EGFR (0.35) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL22912304 | 0.83 | HSD17B10 (0.35) | ALDH1A1VCP | |
| SCHEMBL22912303 | 0.82 | VCP (0.33) | GNRHRVCP | |
| SCHEMBL19806106 | 0.82 | VCP (0.32) | VCP | |
| SCHEMBL22912281 | 0.81 | EGFR (0.36) | KDM4EALDH1A1CYP1A2POLBCYP3A4 | |
| SCHEMBL22912269 | 0.80 | PFKFB3 (0.32) | VCP | |
| SCHEMBL21019945 | 0.80 | BRD4 (0.32) | VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |