Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.31 |
| ▸ | INPP5A | Q14642 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12159803 | 0.85 | INPP5A (0.38) | INPP5A | |
| SCHEMBL12166630 | 0.85 | INPP5A (0.38) | INPP5A | |
| SCHEMBL20832955 | 0.83 | PLG (0.33) | PLGPLATLMNAEPHX2NCF1 | |
| SCHEMBL18869245 | 0.79 | CA1 (0.42) | LMNAINPP5A | |
| SCHEMBL12166836 | 0.79 | CA1 (0.42) | LMNAINPP5A | |
| SCHEMBL10609630 | 0.77 | PLG (0.34) | PLGPLATLMNANCF1 | |
| SCHEMBL10158088 | 0.76 | CYP1A2 (0.42) | LMNA | |
| SCHEMBL12166541 | 0.76 | TRPA1 (0.31) | — | |
| SCHEMBL8287065 | 0.75 | PLG (0.39) | PLGPLATLMNAEPHX2NCF1 | |
| SCHEMBL13598570 | 0.74 | EPHX2 (0.39) | PLGPLATLMNAEPHX2NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |