Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 19/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19805897 | 0.96 | SDHB (0.70) | SDHB | |
| SCHEMBL19805970 | 0.90 | SDHB (0.57) | SDHB | |
| SCHEMBL19805776 | 0.90 | SDHB (0.58) | SDHB | |
| SCHEMBL19805838 | 0.87 | SDHB (0.72) | SDHB | |
| SCHEMBL19805766 | 0.86 | SDHB (0.72) | SDHBMEN1KMT2A | |
| SCHEMBL22912276 | 0.86 | SDHB (0.53) | SDHB | |
| SCHEMBL19806079 | 0.85 | SDHB (0.57) | SDHB | |
| SCHEMBL19805963 | 0.84 | SDHB (0.73) | SDHBMEN1KMT2A | |
| SCHEMBL22912232 | 0.83 | SDHB (0.55) | SDHBMEN1KMT2A | |
| SCHEMBL19805701 | 0.83 | SDHB (0.92) | SDHBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484854-B1 | APOPTOSIS INHIBITORS | NAT INSTITUTE OF BIOLOGICAL SCIENCES BEIJING (CN) | 2021-01-20 | — | — | EP | disclosed |