SCHEMBL22913692

SCHEMBL22913692

c1ccc(-c2nc3ccccc3c3c2ccc2sc4c(-c5cc(-n6c7ccccc7c7ccccc76)cc(-n6c7ccccc7c7ccccc76)c5)cccc4c23)cc1

nearest known ligand 0.31

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NUDT1 P36639 2/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALOX5 P09917 1/20 0.31
PDE10A Q9Y233 1/20 0.31
ALDH1A1 P00352 2/20 0.30
HPGD P15428 2/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
ADORA2A P29274 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22913941 0.88 KDM4E (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL22913307 0.88 KDM4E (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL22913943 0.88 GSR (0.33) KDM4EL3MBTL1NUDT1MEN1POLB
SCHEMBL22913667 0.86 HSD17B10 (0.33) KDM4ENUDT1MEN1POLBKMT2A
SCHEMBL22913582 0.85 ATM (0.34) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL22913584 0.85 NUDT1 (0.36) KDM4EATML3MBTL1NUDT1MEN1
SCHEMBL22913801 0.84 KDM4E (0.32) KDM4EATML3MBTL1NUDT1MEN1
SCHEMBL22914084 0.84 ACACA (0.33) KDM4EL3MBTL1ALOX5ALDH1A1HPGD
SCHEMBL22913842 0.84 MEN1 (0.34) KDM4EATMMEN1KMT2AALOX5
SCHEMBL22913581 0.84 MEN1 (0.38) KDM4EATML3MBTL1NUDT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021015497-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 엘티소재주식회사 2021-01-28 WO disclosed