⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14840392 | 0.88 | — | — | |
| SCHEMBL25218451 | 0.85 | — | — | |
| SCHEMBL22915512 | 0.84 | FDPS (0.41) | — | |
| SCHEMBL3032913 | 0.82 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL21903334 | 0.80 | LMNA (0.46) | — | |
| SCHEMBL21636798 | 0.80 | — | — | |
| SCHEMBL4644554 | 0.80 | — | — | |
| SCHEMBL14966859 | 0.78 | — | — | |
| SCHEMBL4368580 | 0.78 | FDPS (0.44) | — | |
| SCHEMBL5190371 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541050-B2 | Pyrimidine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2023-01-03 | — | — | US | disclosed |
| US-20210023082-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UC (IE) | 2021-01-28 | — | — | US | disclosed |