Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PPM1B | O75688 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22915744 | 1.00 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL16576319 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL21418918 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL20557340 | 0.82 | ALDH1A1 (0.60) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL20721517 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL27195153 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL27195158 | 0.80 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL7048177 | 0.79 | ALDH1A1 (0.56) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL3943578 | 0.78 | ALDH1A1 (0.53) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL7159964 | 0.78 | ALDH1A1 (0.55) | ALDH1A1POLBGAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220251135-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | BEONE MEDICINES I GMBH (CH) | 2022-08-11 | — | — | US | disclosed |
| WO-2021013234-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | BEIGENE, LTD. (KY) | 2021-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220251135-A1 | CYCLIC DINUCLEOTIDES AS STING AGONISTS | STING1, CGAS, MAVS | ALDH1A1 4552/4885POLB 274/4885GAA 1043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.