Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983259 | 0.86 | CYP1A2 (0.34) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL25987473 | 0.81 | — | — | |
| SCHEMBL21726810 | 0.80 | APLNR (0.36) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL24925879 | 0.80 | APLNR (0.36) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL178385 | 0.75 | CYP1A2 (0.36) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL23175337 | 0.74 | MEN1 (0.36) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL22916654 | 0.74 | — | — | |
| SCHEMBL22916392 | 0.72 | — | — | |
| SCHEMBL21134597 | 0.72 | CYP1A2 (0.35) | — | |
| SCHEMBL19012099 | 0.72 | CYP1A2 (0.37) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386978-B1 | BRIDGED PIPERIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2021-01-27 | — | — | EP | disclosed |