Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21726810 | 1.00 | APLNR (0.36) | APLNRMEN1ALDH1A1CYP2D6KMT2A | |
| SCHEMBL21134597 | 0.87 | CYP1A2 (0.35) | APLNR | |
| SCHEMBL178385 | 0.86 | CYP1A2 (0.36) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL765004 | 0.81 | — | — | |
| SCHEMBL1962749 | 0.81 | — | — | |
| SCHEMBL12584762 | 0.80 | — | — | |
| SCHEMBL22916650 | 0.80 | MEN1 (0.33) | MEN1ALDH1A1CYP2D6KMT2ACTDSP1 | |
| SCHEMBL2491416 | 0.79 | APLNR (0.37) | APLNR | |
| SCHEMBL23122419 | 0.77 | CHRM2 (0.38) | APLNR | |
| SCHEMBL16911630 | 0.77 | APLNR (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023003002-A1 | ANNULATED PYRIDAZINE COMPOUND | アステラス製薬株式会社 | 2023-01-26 | — | — | WO | disclosed |