Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 11/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26921704 | 0.90 | — | — | |
| Hydrochloric Acid SCHEMBL25345394 | 0.87 | OPRM1 (0.34) | OPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL29993970 | 0.87 | OPRM1 (0.34) | OPRM1OPRL1 | |
| SCHEMBL25557038 | 0.75 | SLC6A3 (0.39) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL3339369 | 0.74 | — | — | |
| SCHEMBL12844286 | 0.73 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL7457102 | 0.73 | SLC6A3 (0.38) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL18602768 | 0.72 | SLC6A2 (0.32) | SLC6A3SLC6A4SLC6A2OPRM1OPRL1 | |
| SCHEMBL4048080 | 0.72 | USP2 (0.56) | USP2ALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL17583500 | 0.72 | USP2 (0.56) | USP2ALDH1A1LMNACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114929681-B | Bicyclic CX3CR1 receptor agonists | 德州大学系统董事会 | 2024-05-14 | — | — | CN | disclosed |
| CN-114929681-A | Bicyclic CX3CR1 receptor agonists | 德州大学系统董事会 | 2022-08-19 | — | — | CN | disclosed |
| WO-2021016449-A1 | BICYCLIC CX3CR1 RECEPTOR AGONISTS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-01-28 | — | — | WO | disclosed |