SCHEMBL22916751

SCHEMBL22916751

CCCC#Cc1cc(OC)ccc1/C(=C\OC)C(=O)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 5/20 0.41
TAS1R1 Q7RTX1 5/20 0.41
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
HDAC3 O15379 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC2 Q92769 1/20 0.36
ALDH1A1 P00352 3/20 0.35
HPGD P15428 3/20 0.35
KDM4E B2RXH2 2/20 0.35
GAA P10253 2/20 0.35
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
PKM P14618 1/20 0.33
HTT P42858 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31711565 0.93 CTSL (0.45) TAS1R3TAS1R1CTSLCTSBHDAC3
SCHEMBL21427391 0.89 CTSL (0.36) TAS1R3TAS1R1CTSLCTSBHDAC3
SCHEMBL22916683 0.88 MEN1 (0.34) TAS1R3TAS1R1CTSLCTSBALDH1A1
SCHEMBL31711573 0.85 TP53 (0.39) TAS1R3TAS1R1HPGDNPC1RAB9A
SCHEMBL22916689 0.82 MMP1 (0.31)
SCHEMBL31711571 0.80 KDM4E (0.38) CTSLCTSBALDH1A1KDM4ECYP3A4
SCHEMBL22916780 0.78 CYP3A4 (0.36) CTSLCTSBHDAC3HDAC1HDAC2
SCHEMBL25469144 0.75 HAO1 (0.33)
SCHEMBL3163166 0.74 CTSL (0.54) TAS1R3TAS1R1CTSLCTSBHDAC3
SCHEMBL7482556 0.74 KDM4E (0.48) TAS1R3TAS1R1CTSLCTSBHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210022338-A1 ALKYNE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210022338-A1 ALKYNE COMPOUND AND ARTHROPOD PEST CONTROL COMPOSITION CONTAINING SAME C5, C9, C3AR1 TAS1R3 1396/4885TAS1R1 1971/4885CTSL 3414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.