Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 10/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23032061 | 1.00 | AGTR2 (0.68) | AGTR2MEN1KMT2AMAPK1GAA | |
| SCHEMBL23032483 | 0.90 | AGTR2 (0.65) | AGTR2MEN1KMT2AMAPK1GAA | |
| SCHEMBL21399920 | 0.81 | AGTR2 (1.00) | AGTR2 | |
| SCHEMBL23032066 | 0.79 | AGTR2 (0.67) | AGTR2SMN1; SMN2 | |
| SCHEMBL21400000 | 0.79 | AGTR2 (0.85) | AGTR2 | |
| SCHEMBL8685279 | 0.77 | GAA (0.66) | AGTR2MEN1KMT2AMAPK1GAA | |
| SCHEMBL23032373 | 0.76 | AGTR2 (0.76) | AGTR2 | |
| SCHEMBL23032075 | 0.75 | AGTR2 (0.62) | AGTR2 | |
| SCHEMBL22917084 | 0.74 | AGTR2 (0.64) | AGTR2SMN1; SMN2 | |
| SCHEMBL22917552 | 0.72 | AGTR2 (0.47) | AGTR2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |