Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22917280 | 0.77 | AGTR2 (0.68) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL23032061 | 0.77 | AGTR2 (0.68) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL18829414 | 0.77 | ALDH1A1 (1.00) | GAAALDH1A1HPGDUSP2NPSR1 | |
| SCHEMBL14529027 | 0.74 | HRH3 (0.80) | MEN1KMT2AALDH1A1HRH3NPSR1 | |
| SCHEMBL6244724 | 0.73 | ALDH1A1 (0.93) | GAAALDH1A1HPGDUSP2NPSR1 | |
| SCHEMBL5800630 | 0.73 | KDM4E (0.69) | MEN1KMT2AALDH1A1HRH3NPSR1 | |
| SCHEMBL4197501 | 0.73 | KDM4E (0.69) | MEN1KMT2AALDH1A1HRH3NPSR1 | |
| SCHEMBL12300145 | 0.73 | SMN1; SMN2 (0.71) | ALDH1A1HPGDUSP2SMN1; SMN2F2 | |
| SCHEMBL2469546 | 0.73 | ALDH1A1 (0.86) | MEN1KMT2AMAPK1ALDH1A1HPGD | |
| SCHEMBL29675228 | 0.73 | ALDH1A1 (0.86) | MEN1KMT2AMAPK1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5712284-A | Azalicyclooctane derivatives as anti-arrhythmic agents | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1998-01-27 | — | — | US | disclosed |
| EP-0710236-A1 | AZALICYCLOOCTANE DERIVATIVES AS ANTI-ARRHYTHMIC AGENTS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003301-A1 | AZALICYCLOOCTANE DERIVATIVES AS ANTI-ARRHYTHMIC AGENTS | SMITHKLINE BEECHAM LABORATOIRES PHARMACEUTIQUES (FR) | 1995-02-02 | — | — | WO | disclosed |
| EP-0416521-A1 | N-Benzyltropaneamides | G.D. Searle & Co. (US) | 1991-03-13 | — | — | EP | disclosed |