Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429517 | 0.73 | CYP1A2 (0.43) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL29626229 | 0.72 | KDM4E (0.40) | ADORA1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL13206778 | 0.71 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BPTGIRKDM4E | |
| SCHEMBL12555158 | 0.71 | SLC6A2 (0.51) | ADORA1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL11464719 | 0.69 | MAPT (0.41) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL25408527 | 0.68 | KDM4E (0.42) | ADORA1KDM4ECYP1A2MEN1KMT2A | |
| SCHEMBL11558141 | 0.68 | SLC6A2 (0.55) | ADORA1SLC6A2SLC6A4SLC6A3KDM4E | |
| SCHEMBL12500825 | 0.67 | KDM4E (0.41) | KDM4ECYP1A2MEN1KMT2AMAPT | |
| SCHEMBL3905775 | 0.66 | NISCH (0.59) | ADRA1APTGIRCYP1A2CA12CA1 | |
| SCHEMBL4921042 | 0.66 | CYP1A2 (0.43) | KDM4ECYP1A2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3770148-A1 | RECEPTOR INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | Beijing Tide Pharmaceutical Co., Ltd. (CN) | 2021-01-27 | — | — | EP | disclosed |